As Miranda Priestly (Meryl Streep) prepares to step down from her iconic role as editor-in-chief of Runway, rumors swirl about who will inherit her throne. Enter Chloe Devereaux (Florence Pugh), a sharp, fearless fashion influencer who’s determined to disrupt the old guard with her bold, viral vision of what fashion should be.

Meanwhile, Andy Sachs (Anne Hathaway), now a bestselling author and respected journalist, is pulled back into Miranda’s orbit when she’s offered a once-in-a-lifetime opportunity: to write Miranda’s unauthorized biography. But as Andy begins her deep dive into Miranda’s life, she uncovers buried truths, personal regrets, and the emotional cost of a legacy built on perfection.

With Emily Charlton (Emily Blunt) now managing editor and fiercely loyal to Miranda’s vision, tensions rise over loyalty, reinvention, and the future of Runway. As the fashion world faces a generational clash, Miranda must decide whether to protect her empire—or let it evolve.